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Home > Product > Human Lp-PLA2 Antibody (6H3)
Human Lp-PLA2 Antibody (6H3)(Cat. No.:DA059)
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COA
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1mg
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1
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Isotype
Mouse IgG1
Formulation Description
Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
Purity-SDS-PAGE
Greater than 95% as determined by reducing SDS-PAGE.(QC verified)
Bioactivity-BLI
Loaded Human PLA2G7-His(DC624) on HIS1K Biosensor, can bind Human Lp-PLA2 Antibody (6H3)-mFc(DA059) with an affinity constant of <10-3 nM as determined in BLI assay.  (Regularly tested)
Storage
24 months from manufacturing at ≤-20 °C; 1 month, 2 to 8 °C under sterile conditions.
Shipping
The product is shipped on dry ice pack.Upon receipt, store it immediately at the temperature listed below.
Background
Platelet-Activating Factor Acetylhydrolase (PAFAH) is a secreted enzyme which belongs to the AB hydrolase superfamily and Lipase family and catalyzes the degradation of platelet-activating factor to biologically inactive products. PAFAH is produced by inflammatory cells and hydrolyzes oxidised phospholipids in LDL. PAFAH has been implicated in the development of atherosclerosis and has also been identified as a marker for cardiac disease. PAFAH might have a major physiologic effect in the presence of inflammatory bodily responses. PAFAH alters the action of PAF by hydrolyzing the sn-2 ester bond to yield the biologically inactive lyso-PAF. PAFAH has specificity for substrates with a short residue at the sn-2 position.
For Research or Manufacturing Use Only, Not for Use in Diagnostic or Therapeutic Procedures.
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