Home > Product > MPXV H3L Antibody(9E12)
MPXV H3L Antibody(9E12)(Cat. No.:DA128)
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COA
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500μg
1mg
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Isotype
Human IgG1
Mol Mass
49.4&23.4 kDa
APMol Mass
(23-37)&(45-58) kDa, reducing conditions
Formulation Description
Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
Purity-SDS-PAGE
Greater than 95% as determined by reducing SDS-PAGE.(QC verified)
Shipping
The product is shipped on dry ice pack.Upon receipt, store it immediately at the temperature listed below.
Storage
24 months from manufacturing at ≤-20 °C; 1 month, 2 to 8 °C under sterile conditions.
Background
Monkeypox is a zoonotic disease caused by monkeypox virus (MPXV), which is a member of orthopoxvirus genus. A30L protein is required for the association of electron-dense, granular, proteinaceous material with the concave surfaces of crescent membranes, an early step in viral morphogenesis. The H3L protein can be attached to the IMV membrane by its C-terminal hydrophobic structure and bind to HS on the cell surface, promoting viral entry and the H3L protein is a target of cellular immune responses, and the protein exhibits at least two identified human leucocyte antigen (HLA) class I-restricted T-cell epitopes which can elicit robust IFN-γ response. The H3L protein is one of the key targets for MPXV vaccine design.
For Research or Manufacturing Use Only, Not for Use in Diagnostic or Therapeutic Procedures.
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