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Recombinant Human CEA(Cat. No.:DCM95)
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500μg
1mg
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Description
Recombinant Human CEACAM5/CD66e/CEA is produced by Mammalian expression system and the target gene is expressed with a 6His tag at the C-terminus.
Accession
NP_004354.3
Known As
Carcinoembryonic antigen-related cell adhesion molecule 5; Carcinoembryonic antigen; CEA; Meconium antigen 100; CD66e; CEACAM5
Mol Mass
72.4 kDa
APMol Mass
95-150kDa, reducing conditions
Formulation Description
Supplied as a 0.2 μm filtered solution of PBS, pH7.4
Purity-SDS-PAGE
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Storage
  • Reconstituted protein solution should be stored at ≤ -20°C.
  • Stable for at least 24 months when stored as instructed.
Shipping
The product is shipped on dry ice pack.Upon receipt, store it immediately at the temperature listed below.
Background
Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) belong to a group of mammalian immunoglobulin related glycoproteins. They play critical roles in cell–cell recognition. CEACAM5, also called CEA and CD66e, is characterized by having seven extracellular Ig domains and a glycosylphosphatidylinositol (GPI) anchor. CEACAM5 is expressed primarily by epithelial cells, and functions as a calcium-independent adhesion molecule through homophilic and heterophilic interactions with CEACAM1. Studies have shown that CEACAM5 is overexpressed in a majority of carcinomas, and its overexpression can protect tumor cells from apoptosis. It is commonly used as a cancer marker.
For Research or Manufacturing Use Only, Not for Use in Diagnostic or Therapeutic Procedures.
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