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Home > Product > Recombinant Human Jo-1
Recombinant Human Jo-1(Cat. No.:DE045)
DS
COA
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Size：
50μg
500μg
1mg
Count：
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1
+
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Description
Recombinant Human Jo-1 is produced by E.coli expression system and the target gene is expressed .
Accession
P12081
Known As
Histidyl-TRNA Synthetase;HARS;CMT2W;HRS; USH3B;HisRS;Histidine Translase
Mol Mass
57.5 kDa
APMol Mass
50-60 kDa, reducing conditions
Formulation Description
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, 5mM DTT, 10% Glycerol, pH8.0.
Purity-SDS-PAGE
Greater than 85% as determined by reducing SDS-PAGE. (QC verified)
Purity-SEC-HPLC
Greater than 95% as determined by SEC-HPLC.(QC verified)
Bioactivity Data
0
Storage
  • Reconstituted protein solution should be stored at ≤ -20°C.
  • Stable for at least 24 months when stored as instructed.
Shipping
The product is shipped on dry ice pack.Upon receipt, store it immediately at the temperature listed below.
Background
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases. The enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The gene is located in a head-to-head orientation with HARSL on chromosome five, where the homologous genes share a bidirectional promoter. The gene product is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis. Several transcript variants encoding different isoforms have been found for this gene.
For Research or Manufacturing Use Only, Not for Use in Diagnostic or Therapeutic Procedures.
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CRO services for recombinant, protein, antibody, mRNA
Raw materials for molecular diagnostics