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Recombinant Human tTG(Cat. No.:DE056)
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500μg
1mg
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Description
Recombinant Human Tissue Transglutaminase/tTG is produced by E.coli expression system and the target gene is expressed with a 6His tag at the N-terminus.
Accession
P21980
Known As
Tissue transglutaminase;Protein-glutamine gamma-glutamyltransferase 2;TGC;TGM2
Mol Mass
79.5 kDa
APMol Mass
90 kDa, reducing conditions
Formulation Description
Supplied as a 0.2 μm filtered solution of 20mM Citrate, 8% Sucrose, 200mM NaCl, 0.05% Tween80, pH6.0.
Purity-SDS-PAGE
Greater than 90% as determined by reducing SDS-PAGE. (QC verified)
Storage
  • Reconstituted protein solution should be stored at ≤ -20°C.
  • Stable for at least 24 months when stored as instructed.
Shipping
The product is shipped on dry ice pack.Upon receipt, store it immediately at the temperature listed below.
Background
Transglutaminase 2 (TG2), encoded by the TGM2 gene, is also known as tissue transglutaminase (tTG), transgluytaminase C (TGC), and protein‑glutamine‑ gamma -glutamyltransferase. It belongs to the family of transglutaminases that catalyze the posttranslational modification of proteins via calcium dependent cross-linking reactions. In addition to its function in protein cross-linking, TGM2 is also capable of hydrolyzing both GTP and ATP and has intrinsic kinase activity. TGM2 has been implicated in a variety of human diseases including celiac disease, inclusion body myositis, atherosclerosis, and neurodegenerative diseases.
For Research or Manufacturing Use Only, Not for Use in Diagnostic or Therapeutic Procedures.
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