Recombinant CAdV-1(strain RI261) Fiber protein is produced by our E.coli expression system and the target gene encoding Thr365-Gln543 is expressed with a 6His tag at N-terminus.

Fiber protein; Fiber; SPIKE; Protein IV; L5

21.1 KDa

18-21 kDa, reducing conditions

Supplied as a 0.2 μm filtered solution of PBS, pH7.4.

The product is shipped on dry ice pack.Upon receipt, store it immediately at the temperature listed below.

Canine adenovirus (CAdV), a member of the Mastadenovirus genus of the Adenoviridae family, is one of the pathogens causing severe viral diseases in dogs worldwide. CAdVs are classified into two types: CAdV type 1 (CAdV-1), which causes canine infectious hepatitis and fox encephalitis, and CAdV type 2 (CAdV-2), which causes infectious laryngotracheitis and enteritis. CAdV-2 differs from CAdV-1 in virulence, antigen structure, infection ability, and erythrocyte aggregation range. Dogs infected with CAdV-2 show persistent high fever, cough, and other clinical manifestations, such as mucinous rhinorrhea, tonsillitis, laryngotracheitis, pneumonia, vomiting, and diarrhea. CAdV-2 is one of the main pathogens that cause canine viral enteritis. Here are three major capsid proteins encoded by CAdV—Fiber, Hexon, and Penton. denoviral Fiber protein plays a crucial role in infection by attaching the virus to a specific cell surface receptor, whereas the Penton base is responsible for virus internalization.