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Recombinant Human IL-15(Cat. No.:GMP-C016)
DS
COA
Price：
Size：
50μg
500μg
1mg
Count：
-
1
+
First Classification
Gene and Cell Therapy
Datasheet
GMP-C016-EN.pdf
Catalog Number
GMP-C016
Product Name
Recombinant Human IL-15
Description
  • Il-15 (Interleukin-15), is a member of the Il-2 cytokines family. Il-15 performs biological functions by γ c receptor subunits. Several therapies targeting solid tumor and blood cell tumor have entered the clinic study. Although both IL-2 and IL-15 are involved in early T cell proliferation and activation. The antitumor activity of IL-15 also comes from direct activation of CD8+ effector T cells in a non-specific antigen immunogenicity way. It is reported that there has been clinic study of IL-15 targeting immune cell therapy entering phase I.
  • This product is from a large scale GMP leveled Recombinant Human Il-15 production via E. coli expression. Applying pharmaceutical leveled adjuvants and materials for production, strictly controlling host protein residues, nucleic acid residues, pathogene contamination and other impurities, we guarantee an auditable manufacture and quality control practice complying to GMP regulation, as well as all the materials traceable.
Accession
P40933
Quality Control
ItemStandard
AppearanceSolidoid, white porosity
ReconstitutionTotally dissolve in stated time
Visible particleConform to ChP
pH value6.5-7.5
Purity≥ 95%
Bioactivity≥ 1.0×107 IU/mg
Endotoxin< 10 EU/mg
Host protein≤ 0.005%
Exogenous DNA residue≤ 10 ng/mg
Mycoplasma testNegative
Sterility testConform to ChP
Usage
In-vitro cultivation of various types of cell
Storage
Storage at -20±5℃, expiration date labeled on bottle.
Shipping
Lyophilized product in powder form, 2-8℃ temperature required for transport
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Second Classification
GMP Grade Cytokines
Protein Species
Human
Source
E.coli
Protein Expression Range
Asn49-Ser162
Tag
Tag free
Abbreviation
IL-15
Recommendations
  • （1）Make sure the product properly stored and none expired before using.
  • （2）Please use water for injection for reconstitution, to a concentration > 100 μg/ml.
  • （3）Sterile condition without pyrogen is required for reconstitution, re-aliquoting, dilution.
  • （4）After reconstitution, aliquoted solution vials should be stored at -70°C and minimize freeze-thaw cycles preventing denaturation of protein.
Size/Price
50μg/$573500μg/Inquiry1mg/Inquiry
Bioactivity-Cell Based Assay
Measured in a cell proliferation assay using CTLL-2 mouse cytotoxic T cells. The specific activity of Recombinant human IL-15 is ≥ 1.0 × 107 IU/mg. which is calibrated against human IL-15 WHO International Standard (NIBSC code: 95/554)
The activity of GMP Human IL-15 Protein(Cat. No.:GMP-C016) was compared to another commercially available product.
Highest Abbreviation
Human IL-15
URLClassification
Gene and Cell Therapy,,GMP Grade Cytokines,,N/A
Priority Level
17
Key Words
Interleukin-15IL-15IL15
Language Code
English
Formulation
0
Product Status
1
仅供科研或生产使用，不可直接应用于人体。
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