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Recombinant Human IL-7(Cat. No.:GMP-CD47)
DS
COA
Price：
Size：
50μg
500μg
1mg
Count：
-
1
+
First Classification
Gene and Cell Therapy
Key Words
Interleukin-7IL-7IL7
Language Code
English
Accession
P13232
Shipping
Lyophilized product in powder form, 2-8℃ temperature required for transport
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Protein Species
Human
Source
Human Cells
Protein Expression Range
Asp26-His177
Tag
C-6His
Abbreviation
IL-7
Highest Abbreviation
Human IL-7
Recommendations
  • （1）Make sure the product properly stored and none expired before using.
  • （2）Please use water for injection for reconstitution, to a concentration > 100 μg/ml.
  • （3）Sterile condition without pyrogen is required for reconstitution, re-aliquoting, dilution.
  • （4）After reconstitution, aliquoted solution vials should be stored at -70°C and minimize freeze-thaw cycles preventing denaturation of protein.
URLClassification
Gene and Cell Therapy,,GMP Grade Cytokines,,N/A
Priority Level
36
Second Classification
GMP Grade Cytokines
Catalog Number
GMP-CD47
Product Name
Recombinant Human IL-7
Description
  • Interleukin-7 (IL-7), a member of the cytokine family related to IL-2, stimulates the survival, proliferation, and homeostasis of T cells via the gamma c (γc) subunit of the receptor. IL-7 can replace IL-2 for activating T cells and avoid the immune tolerance due to Treg activation by IL-2. Studies have shown that IL-7 can expand antigen-specific T cells in vaccine injection or cell therapy; in addition, IL-7 is able to promote T cell recovery after chemotherapy or hematopoietic stem cell transplant.
  • Recombinant Human IL-7 is expressed by mammalian cells, and is produced with raw materials of pharmaceutical applicable level. The host protein residue, nucleic acid residue and common pathogens are strictly controlled, and the production and quality management procedures of the product comply with GMP regulations to ensure the traceability of the production process and all raw materials.
Quality Control
ItemStandard
AppearanceWhite porosity
ReconstitutionTotally dissolve in stated time
Visible particleConform to ChP
pH value6.9–7.9
Purity≥ 95%
Bioactivity≥ 1.0×108 IU/mg
Endotoxin< 10 EU/mg
Host protein≤ 0.005%
Exogenous DNA residue≤ 100 pg/mg
Mycoplasma testNegative
Sterility testConform to ChP
Usage
  • In-vitro cultivation of various types of cell.
  • IL-7 can replace IL-2 (Cat. No.: GMP-C013) for activating T cells and can avoid immune tolerance due to Treg activation by IL-2.
Storage
Storage at -20℃, expiration date labeled on bottle.
Product stability
Recombinant human IL-7 stimulates proliferation of PHA-activated human peripheral blood lymphocytes.The specific activity is ≥ 1.0 × 108 IU/mg.Three independent lots were tested for activity and plotted on the same graph to show lot-to-lot consistency of IL-7.
Datasheet
GMP-CD47-EN.pdf
Bioactivity-Cell Based Assay
Measured in a cell proliferation assay using PHA-activated human peripheral blood lymphocytes (PBL).The specific activity of Recombinant human IL-7 is ≥ 1.0 × 108 IU/mg, which is calibrated against human IL-7 WHO International Standard (NIBSC code: 90/530)
Size/Price
50μg/$573500μg/Inquiry1mg/Inquiry
Formulation
0
Product Status
1
仅供科研或生产使用，不可直接应用于人体。
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