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Recombinant Human IL-2(Cat. No.:GMP-CD66)
DS
COA
Price：
Size：
50μg
500μg
1mg
Count：
-
1
+
Tag
C-6His
Accession
P60568
Shipping
Lyophilized product in powder form, 2-8℃ temperature required for transport
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Protein Species
Human
Source
Human Cells
Abbreviation
IL-2
Priority Level
62
Protein Expression Range
Ala21-Thr153
Catalog Number
GMP-CD66
Product Name
Recombinant Human IL-2
Highest Abbreviation
Human IL-2
URLClassification
Gene and Cell Therapy,,GMP Grade Cytokines,,N/A
Key Words
Interleukin-2IL-2T-Cell Growth FactorTCGFIL2
Language Code
English
Usage
In-vitro cultivation of various types of cells.
Storage
Storage at -20℃, expiration date labeled on bottle.
Description
  • IL-2, also known as T cell growth factor (TCGF), is the most important cytokine that causes T cell proliferation. IL-2 specifically binds to the IL-2 receptor (IL-2R) on the surface of T cells to activate T cells, for proliferation. Besides, IL-2 stimulates the growth of NK cells and enhances lethality of NK cells. IL-2, together with other T cell growth factors from the family activates and duplicates CD4+ and CD8+T cells by the common receptors.
  • IL-2 activates T cells and NK cells by autocrine and paracrine modes. Unlike T cells, NK cells do not express alpha receptor subunit and therefore have a low affinity for IL-2. However, IL-2 can promote NK cell proliferation, enhance cell activity and generating other cytokines. B cells are also activated by IL-2, which leads to proliferation and cell differentiation.
  • Recombinant Human IL-2 is expressed by mammalian cells, and is produced with raw materials of pharmaceutical applicable level. The host protein residue, nucleic acid residue and common pathogens are strictly controlled, and the production and quality management procedures of the product comply with GMP regulations to ensure the traceability of the production process and all raw materials.
Quality Control
ItemStandard
AppearanceWhite porosity
ReconstitutionTotally dissolve in stated time
Visible particleConform to ChP
pH value6.9–7.9
Purity≥ 95%
Bioactivity≥ 1.0×107 IU/mg
Endotoxin< 10 EU/mg
Host protein≤ 0.005%
Exogenous DNA residue≤ 100 pg/mg
Mycoplasma testNegative
Sterility testConform to ChP
Datasheet
GMP-CD66-EN.pdf
First Classification
Gene and Cell Therapy
Second Classification
GMP Grade Cytokines
Recommendations
  • （1）Make sure the product properly stored and none expired before using.
  • （2）Please use water for injection for reconstitution, to a concentration > 100 μg/ml.
  • （3）Sterile condition without pyrogen is required for reconstitution, re-aliquoting, dilution.
  • （4）After reconstitution, aliquoted solution vials should be stored at -70°C and minimize freeze-thaw cycles preventing denaturation of protein.
Size/Price
50μg/$188500μg/Inquiry1mg/Inquiry
Formulation
0
Product Status
1
仅供科研或生产使用，不可直接应用于人体。
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