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Recombinant Human IL-18(Cat. No.:GMP-CD72)
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COA
Price：
Size：
50μg
500μg
1mg
Count：
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1
+
Shipping
Lyophilized product in powder form, 2-8℃ temperature required for transport
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Protein Species
Human
Accession
Q14116
Description
  • Interleukin-18 (IL-18) is a member of the IL-1 family. Its ability to induce the production of IFN-gamma is even stronger than IL-12. IL-18 can stimulate the proliferation of CD3 monoclonal antibody-activated T cells. It also acts as an activator of NK cells to enhance the cytotoxic effect of NK cells. Also, IL-18 can act synergistically with IL-12 to induce the production of IFN-gamma, improving NK cell activity and promoting T cell proliferation.
  • Recombinant Human IL-18 is expressed by mammalian cells, and is produced with raw materials of pharmaceutical applicable level. The host protein residue, nucleic acid residue and common pathogens are strictly controlled, and the production and quality management procedures of the product comply with GMP regulations to ensure the traceability of the production process and all raw materials.
Quality Control
ItemStandard
AppearanceWhite porosity
ReconstitutionTotally dissolve in stated time
Visible particleConform to ChP
pH value6.9–7.9
Purity≥ 95%
Bioactivity≥ 1.0×107 IU/mg
Endotoxin< 10 EU/mg
Host protein≤ 0.005%
Exogenous DNA residue≤ 100 pg/mg
Mycoplasma testNegative
Sterility testConform to ChP
Usage
  • In-vitro cultivation of various types of cell
  • IL-18 can act synergistically with IL-12 (Cat. No.: GMP-CI58) to induce the production of IFN-gamma, improving NK cell activity and promoting T cell proliferation.
Storage
Storage at -20℃, expiration date labeled on bottle.
Datasheet
GMP-CD72-EN.pdf
First Classification
Gene and Cell Therapy
Second Classification
GMP Grade Cytokines
Source
Human Cells
Recommendations
  • （1）Make sure the product properly stored and none expired before using.
  • （2）Please use water for injection for reconstitution, to a concentration > 100 μg/ml.
  • （3）Sterile condition without pyrogen is required for reconstitution, re-aliquoting, dilution.
  • （4）After reconstitution, aliquoted solution vials should be stored at -70°C and minimize freeze-thaw cycles preventing denaturation of protein.
URLClassification
Gene and Cell Therapy,,GMP Grade Cytokines,,N/A
Key Words
Interleukin-18IboctadekinInterferon gamma-inducing factorIFN-gamma-inducing factorInterleukin-1 gammaIL-1 gammaGIFIL-18IL-1gIL1F4MGC12320IL18
Language Code
English
Highest Abbreviation
Human IL-18
Priority Level
83
Protein Expression Range
Tyr37-Asp193
Tag
C-6His
Abbreviation
IL-18
Catalog Number
GMP-CD72
Product Name
Recombinant Human IL-18
Size/Price
50μg/$413500μg/Inquiry1mg/Inquiry
Formulation
0
Product Status
1
仅供科研或生产使用，不可直接应用于人体。
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